Interactive histograms of the estimated fitness effects of different types of mutations. Mutations are stratified by whether they are nonsynonymous, synonymous, or introduce a stop codon. Mutations with negative fitness effects are deleterious.
The minimum expected count slider below the plot indicates how many expected counts of a mutation we require before making a fitness estimate. Larger values yield more accurate estimates but for fewer mutations. Move the slider to the left to show estimates for more mutations at lower confidence, and move it to the right to show estimates for fewer mutations at higher confidence. Values in a range of 10 to 20 are usually sufficient to yield reasonably accurate estimates.
You can click/shift-click on specific genes in the legend below the plot to show only estimates for those genes.
See https://github.com/jbloomlab/SARS2-mut-fitness for full computer code and data.
See https://jbloomlab.github.io/SARS2-mut-fitness/ for links to all interactive plots.